Pharmaceutical research

Shalgunov, V.; Dierckx, R. A. J. O.; Elsinga, P. H.; van, W. J.-P.; Booij, J.; Janssen, H. M.; Fransen, P. M.; Michel, M. C. Synthesis and evaluation in rats of the dopamine D2/3 receptor agonist 18F-AMC20 as a potential radioligand for PET. J Nucl Med 2015, 56, 133-139.

Shalgunov, V.; van Wieringen, J.-P.; Janssen, H. M.; Fransen, P. M.; Dierckx, R. A. J. O.; Michel, M. C.; Booij, J.; Elsinga, P. H. Synthesis and evaluation in rats of homologous series of [18F]-labeled dopamine D2/3 receptor agonists based on the 2-aminomethylchroman scaffold as potential PET tracers. EJNMMI Research 2015, 5 (1), 1-13.

Versteegen, R. M.; Rossin, R.; ten Hoeve, W.; Janssen, H. M.; Robillard, M. S. Click to Release: Instantaneous Doxorubicin Elimination upon Tetrazine Ligation. Chem., Int. Ed. 2013, 52, 14112-14116.

van den Bosch, S. M.; Rossin, R.; Renart Verkerk, P.; ten Hoeve, W.; Janssen, H. M.; Lub, J.; Robillard, M. S. Evaluation of strained alkynes for Cu-free click reaction in live mice. Med. Biol. 2013, 40, 415-423.

Rossin, R.; van den Bosch, S. M.; ten Hoeve, W.; Carvelli, M.; Versteegen, R. M.; Lub, J.; Robillard, M. S. Highly Reactive trans-Cyclooctene Tags with Improved Stability for Diels-Alder Chemistry in Living Systems. Bioconjugate Chem. 2013, 24, 1210-1217.

Gianella, A.; Mieszawska, A. J.; Hoeben, F. J. M.; Janssen, H. M.; Jarzyna, P. A.; Cormode, D. P.; Costa, K. D.; Rao, S.; Farokhzad, O. C.; Langer, R.; et al. Synthesis and in vitro evaluation of a multifunctional and surface-switchable nanoemulsion platform. Chem. Commun. 2013, 49, 9392-9394.

Roumen, L.; Peeters, J. W.; Emmen, J. M. A.; Beugels, I. P. E.; Custers, E. M. G.; de, G. M.; Plate, R.; Pieterse, K.; Hilbers, P. A. J.; Smits, J. F. M.; et al. Synthesis, biological evaluation, and molecular modeling of 1-benzyl-1H-imidazoles as selective inhibitors of aldosterone synthase (CYP11B2). J Med Chem 2010, 53, 1712-1725.